2019 Colorado Alphaherpesvirus Latency Society symposium
نویسندگان
چکیده
منابع مشابه
Interferon Alpha Induces Establishment of Alphaherpesvirus Latency in Sensory Neurons In Vitro
BACKGROUND Several alphaherpesviruses, including herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), establish lifelong latency in neurons of the trigeminal ganglion (TG). Although it is thought that efficient establishment of alphaherpesvirus latency is based on a subtle interplay between virus, neurons and the immune system, it is not clear which immune components are of major import...
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Marek's disease virus (MDV) is an alphaherpesvirus that causes deadly T-cell lymphomas in chickens and serves as a natural small animal model for virus-induced tumor formation. In vivo, MDV lytically replicates in B cells that transfer the virus to T cells in which the virus establishes latency. MDV also malignantly transforms CD4+ T cells with a T(reg) signature, ultimately resulting in deadly...
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ژورنال
عنوان ژورنال: Journal of NeuroVirology
سال: 2019
ISSN: 1355-0284,1538-2443
DOI: 10.1007/s13365-019-00798-z